Infectious complications after post‐transplantation cyclophosphamide and anti‐thymocyte globulin‐based haploidentical stem cell transplantation
نویسندگان
چکیده
منابع مشابه
Comparable Outcomes for Hematologic Malignancies after HLA-Haploidentical Transplantation with Posttransplantation Cyclophosphamide and HLA-Matched Transplantation
The implementation of high-dose posttransplantation cyclophosphamide (PTCy) has made HLA-haploidentical (haplo) blood or marrow transplantation (BMT) a cost effective and safe alternative donor transplantation technique, resulting in its increasing utilization over the last decade. We review the available retrospective comparisons of haplo BMT with PTCy and HLA-matched BMT in adults with hemato...
متن کاملInfectious complications in cord blood and T-cell depleted haploidentical stem cell transplantation.
Infections due to post transplant immune deficiency is a major problem following allogeneic stem cell transplantation, particularly in patients receiving cord blood or T-cell depleted haploidentical transplants. We evaluated the incidence and type of infectious complications that occurred in these two types of transplant for 65 patients, 37 cord blood and 28 haploidentical, who received the sam...
متن کاملInfectious Complications of Hematopoietic Stem Cell Transplantation
Hematopoietic stem cell transplantation (HSCT) has been one of the revolutionary discoveries in the world of science leading to cure of many of the hematological malignancies and for several nonmalignant conditions. It involves harvesting of stem cells from either the bone marrow most traditionally, peripheral blood or umbilical cord and then transplanting them into a recipient [1-3]. This coul...
متن کاملOsteoporosis after stem cell transplantation
Background Stem cell transplantation has become as a novel treatment for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. Improved survival of transplant recipients has raised awareness of post-transplant complications. One of these complications is transplant-related osteoporosis. Methods In this manuscript we review prevention methods for transplant-relat...
متن کاملAn overview of conditioning regimens for haploidentical stem cell transplantation with post-transplantation cyclophosphamide.
Haploidentical related donors are an attractive alternative source of stem cells for allogeneic stem cell transplantation due to widespread availability and ease of stem cell procurement. Historically, haploidentical stem cell transplantation (HaploSCT) with extensive T-cell depletion has been associated with high rates of infectious complications and nonrelapse mortality (NRM). Post-transplant...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2019
ISSN: 0007-1048,1365-2141
DOI: 10.1111/bjh.16189